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pentobarbital will minimize the extent or influence of fostemsavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.Barbiturates can induce hepatic microsomal enzymes leading to improved metabolism and lowered anticoagulant response of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); individu